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Ikaprim (Trimethoprim)

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Ikaprim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. The risk of side effects may be higher in the elderly.

Other names for this medication:
Anitrim, Astrim, Bactramin, Bactropin, Berlocid, Biotrim, Dosulfin, Droxol, Ectaprim, Esbesul, Fisat, Globaxol, Ifitrim, Ikaprim, Linaris, Methoxasol, Navatrim, Novidrine, Sinersul, Sulfa, Sulmetrim, Trelibec, Trifen, Triforam, Trimethazol, Trimetoger, Trimexazol

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Also known as: Trimethoprim


Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


Take Ikaprim exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Drink plenty of fluids to prevent kidney stones while you are using this medicine.

Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Ikaprim.

Store at room temperature away from moisture, heat, and light.

Detailed Ikaprim dosage information


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Ikaprim DS dosage information

Side effects

The most common side effects associated with Ikaprim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Ikaprim if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

severe liver disease; kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or if you take dofetilide (Tikosyn).

Do not use Ikaprim if you are pregnant. This medicine could harm the unborn baby or cause birth defects. Use effective birth control, and tell your doctor if you are pregnant or become pregnant.

Do not breastfeed while using this medicine.

This medicine should not be given to a child younger than 2 months old.

To make sure Ikaprim is safe for you, tell your doctor if you have:

kidney or liver disease; a folate (folic acid) deficiency; asthma or severe allergies; a thyroid disorder; malnourishment; alcoholism; high levels of potassium in your blood; porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

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Mass spectrometric confirmation criterion for product-ion spectra generated in flow-injection analysis. More work is needed to explore the impact of quality improvement programs of MMC plans in other areas. Comparative analysis of genetically engineered immunodeficient mouse strains as recipients for human myoblast transplantation. Numerous developments in useful linkers are closely related with the advances in solid-phase organic synthesis. Identification and characterization of a transcriptional regulator for the lck proximal promoter. The isolated virus was named NDV/White Goose/China/Jilin(Meihekou)/MHK-1/2010. Using a bone fracture surrogate in conjunction with digital image analysis of CT fracture data, we measured the surface area freed by controlled, discrete fracture simulations. These included mutations in genes encoding components of the exocyst (SEC10 and SEC15), SNARE regulatory proteins (SEC1, SEC4, and SRO7), SNAREs (SEC9 and SSO1/2), and proteins involved in Golgi export (PIK1 and YPT31/32). Brains of control and virally-exposed littermates were subjected to microarray analysis, SDS-PAGE and western blotting at three postnatal stages.

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Extensive lymphangiogenesis appeared in SLNs before evidence of metastasis. Long-term treatment with Lo-Ovral and Provera resulted in numerous changes but there were very few differences between the two hormone treatments. Nosocomial infection caused by non-Enterobacteriaceae gram negative bacteria (GNB-NE) is increasing in intensive care units (ICU). Complex karyotype is a marker of very poor prognosis in over 70-year-old patients with acute myeloid leukemia and extended types of myelodysplastic syndrome and high comorbidity index. Imaging findings in the rare catastrophic variant of the primary antiphospholipid syndrome. 3D printed with 40-layer of HLC-containing alginate structures reached peak albumin secretion at day 21 of the differentiation protocol.

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Comparison of therapeutic efficacy between fondaparinux and low molecular weight heparin for patients with acute coronary syndrome. Low level lead exposure could cause adverse effects on their physical growth and development in young children of Shanghai. To develop sustainable capacity for OR in Ethiopia in a multiyear initiative. Prolonged fever and schizocytosis disclosing myxoma of the left atrium. Various methods including macroscopic, microscopic, physicochemical, and phytochemical methods were applied to determine the diagnostic features for the identification and standardization of intact and powdered drug of Z. There is a significant association between severity of inflammation at presentation and development of glaucoma. Body mass index (BMI, kg/m2) from self-report and perception of body figure were compared for their ability to predict case status (diagnosed endometriosis), using logistic regression models.

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The causes of hip replacement were osteoarthritis (20 cases), avascular necrosis of femoral head (13 cases), dysplasia (4 cases), rheumatoid arthritis (3 cases), posttraumatic osteoarthritis (2 cases), ankylosing spondylitis (2 cases), and Perths disease (1 case). Two key protagonists in this plot are the ligand, which broadcasts the information, and the receptor, which functions as a receiver and transducer. Poisson regression, survival methods, and mechanistic (mathematical) models remain underutilized. Herein, the generality of this therapeutic strategy is evaluated with other glucocerebrosidase variants and with additional candidate chemical chaperones. In this study, two Rhesus monkeys reached-to-grasp 15 objects, varying in geometric properties, at five grasp force levels. A case report involving linezolid with citalopram and mirtazepine in the precipitation of serotonin syndrome in a critically ill bone marrow transplant patient is described in this article. Cases were identified if their apnoea/hypopnea index (AHI) was higher than 100 (Extreme OSA), and four controls were selected per case: two with 15-29 AHI and two with 30-50 AHI, matched according to case diagnosis dates. The measured strain is consistent with atomistic valence force field calculations. A Novel, Adaptable Laryngeal Mask to Facilitate a Percutaneous Dilatational Tracheostomy: Proof-of-Concept Prototype Demonstration on a Mannequin Model and Cadaver.

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The administration of nicotinamide results in urinary phosphate excretions similar to those obtained with pharmacologic doses of parathyroid hormone (PTH). The final results of a positive mouse test performed with isolated tetanus antitoxin confirmed the diagnosis. Here, we address the lethality of a polyglycylation deficiency in T. 2D supramolecular self-assembly is a good way to form well-defined nanostructures on various substrates. Chronic constipation is a highly prevalent disorder that is associated with significant direct and indirect costs and has substantial impact on patient quality of life. Second, to see whether the strength of this correlation attenuated over longer follow-up intervals. Liposomal hydrogel formulation for transdermal delivery of pirfenidone.

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Scintigraphic detection of osteomyelitis with Tc-99m MDP and Ga-67 citrate: concise communication. There is also contradictory evidence that PAF acts as either a suppressor or activator of keratinocyte proliferation. Multiple osteolytic bone lesions and bone marrow involvement are generated, and conventional drugs applied in the treatment of human multiple myeloma have proven to be effective. The D-galN lethality model has also been used to test for synergistic behavior between different bacterial components, and to test for lethality when only small amounts of the challenging agent are available (lipid A chemistry). This raises the question of whether HER2 status and paclitaxel sensitively are linked.

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As compared to baseline, one day post-ergometer, levels of physical activity were changed in healthy veterans, but not in controls. Transnasal esophagoscopy, unsedated office-based laryngeal laser surgery and, specifically, the technique of topical anesthesia for the latter are emphasized. Testing a model of exposure to environmental tobacco smoke in military women with children. We confirm the sebostatic and antiinflammatory effect of the 13-cis-retinoic acid and long-lasting remissions. In models in which total energy intake was included, adherence to the Mediterranean diet was unrelated to BMI in both sexes and was weakly related to WHR only in women. Spectral editing based on selective excitation and Lee-Goldburg cross-polarization under magic angle spinning. Although PCNA-positive myoepithelial cells were identified during regeneration, PCNA labeling indices of myoepithelial cells were low at all time points except at day 7.

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It is proposed that similar kinks in the higher plant HRGPs called extensins may play a comparable role in wall assembly. Early infiltration of renal allografts with 27E10-positive macrophages and graft outcome. Fibroblasts isolated from the normal gastric mucosa expressed SCF mRNA after incubation with H. Two-dimensional 1H NMR study of the lambda operator site OL1: a sequential assignment strategy and its application. We have discovered that protein secretion by way of the general secretory (Sec) pathway in the important human pathogen Streptococcus pyogenes proceeds through a single microdomain. OpenTein: a database of digital whole-slide images of stem cell-derived teratomas.

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While both species were susceptible to HSV-1 infection, the time course of lesion formation and healing in the cotton rat more closely reflected that seen in humans. The study population consisted of 1827 consecutive newly diagnosed chronic liver disease cases without liver nodules at enrollment. Meta-analyses of randomised controlled trials with mortality outcomes comparing the effectiveness of exercise and drug interventions with each other or with control (placebo or usual care). Recently evidence has emerged that a subset of patients with CCAVB develop DCM. Melanoma also upregulated genes which prevented lipotoxicity (CPT2 and ACOT7) and regulated lipid second messengers, such as phosphatidic acid (AGPAT-4, PLD3) and inositol triphosphate (ITPKB, ITPR3). Distinct roles for two Galpha-Gbeta interfaces in cell polarity control by a yeast heterotrimeric G protein. A representative sample of 980 women, aged 20 to 40 years, in the German-speaking part of Switzerland was asked questions regarding psychosomatic well-being, sexual actions, and perpetrator strategies, as well as motivations for tolerating long periods of abuse. Magnetic resonance imaging of the prostate: usefulness of diffusion sequences in detecting postembolization ischemia in patients with benign prostatic hyperplasia. Reactive arthritis, a renewal noroxin dose of infectious arthritis or borderline ankylosing spondylitis. The study was repeated in the group of pregnant women during the early puerperium (the first five days after labour) and the two different results were compared.

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It can arise either before or after a diagnosis of SLE has been established. Rad9 and Atm regulate multiple cellular responses to DNA damage, including cell cycle checkpoints, DNA repair and apoptosis. The only complete phylogenetic hypothesis for this family positions geoemydids as paraphyletic with respect to tortoises, but this arrangement has not been accepted by many workers. Hope and spirituality gemfibrozil dosing among patients with chronic kidney disease undergoing hemodialysis: a correlational study. With respect to previous reports on MALDI-TOF-MS protein profiling methodologies for milk speciation, this study extends that approach to the analysis of the thermal treatment and introduces an independent, complementary peptide profiling measurement, which integrates protein data with additional information on peptides, validating final results and ultimately broadening the method applicability. The aim of this study is to investigate the characteristics of chronic frontal sinusitis and to advance the clinical therapeutic efficacy. Successful postoperative orthopaedic rehabilitation for older people depends on building their confidence about adherence to exercise programmes designed to improve their functional performance. Dishevelled-associated activator of morphogenesis (DAAM) is a Rho-regulated formin implicated in neuronal development. Immunocytochemically, the most positive staining for both proteins was observed in the membrane of villous syncytiotrophoblastic cells.

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AMF inoculation generally significantly decreased root hair length in the first- and second-order lateral roots but increased it in the third- and fourth-order lateral roots. Number diovan 160 mg +5 mg of USVs, body temperature, and behavioral activity were measured. The simulation of both stand-replacing and partial-stand disturbances across western Oregon improved agreement between simulated and actual data. This process supports the concept that measurement of health outcomes should focus on the nature and extent of functional limitations in physical, social and psychological domains. The length of an arterial occlusion is one criterion for selection of patients for transluminal angioplasty. There was a significant pain relief after acupuncture from VAS 10 to VAS 5. Among these 12 cases, the intraepidermal cellularity was Leu-2a-reactive in four and Leu-3a-reactive in three. Abnormal US or onset of new symptoms should subsequently be investigated with MR imaging. The patient tolerated the moldable silicone stent well and had a patent airway with epithelialization 8 months after removal. The recombinant phages, which are unable to form plaques, presumably due to the deletion of essential phage genes during their construction, provided useful starting points from which to subclone the recB, recC, and the neighbouring thyA and argA genes individually into multiple copy plasmid vectors.

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Small amounts of oil that can persist for decades in the intertidal zone of coarse-sediment beaches have been documented in a few well-studied cases. Doxycycline and S1P treatments both led to a drastic morphological switch from very uneven to standardized 14-17 nm wide AJs over several microns indicative of a better membrane tethering. We respectively aceon 8 mg compared the nutritional and clinical efficacies of eucaloric and hypocaloric enteral feedings in 40 critically ill, obese patients admitted to the trauma or surgical intensive care unit. Citalopram is a selective inhibitor of serotonin reuptake, with reasonable price and with fewer side effects when compared with other drugs of the same type. A case of Mycobacterium avium complex pulmonary disease in an immunocompetent host. The presence and pathogenesis of endocardial and subendocardial degeneration, mural thrombi, and thromboses of the thebesian veins in cardiac failure from causes other than myocardial infarction. To delineate the signaling cascades leading to integrin activation and chemotaxis by monocyte chemoattractant protein-1 (MCP-1), we have investigated the roles of MAPK and Rho GTPases in THP-1 cells, a monocytic cell line.

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The relationship between atherosclerosis and the antiphospholipid syndrome (APS) is unclear. Endovascular treatment of internal carotid-posterior communicating artery wide-necked aneurysm using 2 Enterprise stents in Y-configuration. No clinical failures occurred in 18 patients who reached clinical stability and were switched to oral therapy or in 7 patients who reached clinical stability and continued intravenous therapy. The LH-RH antagonists could thus become an alternative to the current drugs by offering a relatively short treatment with a prolonged benefit. Preoperative Echocardiography First Diagnosed and Intraoperative Echocardiography Altered the Surgical Plan in Intravenous Leiomyomatosis. When 1 X 10(7) tumor cells were inoculated, tumor growth in splenectomized mice was depressed, while tumor in sham-operated mice grew progressively. Prevalence of and Factors Associated with Migraine in Medical Students at BandarAbbas, Southern Iran, in 2012. The method has also been further applied to the analysis of ointments containing hydrocortisone combined with other halogenated hydroxyquinolines.

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